Fresh hope in pancreatic cancer war

 

Pancreatic cancer cells can be destroyed by combining two drugs, researchers have found - giving hope that more effective treatments can be developed to combat the disease. The research by Cancer Research UK's Cambridge Research Institute showed in mice that combining a chemotherapy drug called gemcitabine with an experimental drug called MRK003 sets off a chain of events that ultimately kills cancer cells - multiplying the effect of each drug on its own. MRK003 blocks an important cell signalling pathway called Notch in both pancreatic cancer cells and the endothelial cells that line the blood vessels supplying tumours with essential nutrients. Experts found the addition of MRK003 to gemcitabine - a drug used commonly in patients with pancreatic cancer - increased the ability of gemcitabine to destroy tumours. The research was published in the Journal of Experimental Medicin, and study author Professor David Tuveson said: "We've discovered why these two drugs together set off a domino effect of molecular activity to switch off cell survival processes and destroy pancreatic cancer cells." Around 8,000 people in the UK are diagnosed with pancreatic cancer each year and the disease is the fifth most common cause of cancer death in the UK. Survival rates are very low in relation to other cancers and the length of time between diagnosis and death is typically short, usually less than six months. The most recent data for England show that around 16% of patients survive their disease beyond 12 months after diagnosis - prompting the need for new treatments. The discovery is now a clinical trial being led by Duncan Jodrell, professor of cancer therapeutics at the University of Cambridge. He said: "We're delighted that the results of this important research are now being evaluated in a clinical trial, to test whether this might be a new treatment approach for patients with pancreatic cancer, although it will be some time before we're able to say how successful this will be in patients."

Alastair Campbell on drink: 'I paid a heavy price'

 

Alastair Campbell, Tony Blair's former spokesman, examines the British middle class's troubled relationship with alcohol and his own long and complicated history with drink. To read the headlines about Britain's drink problem, you might think it is largely an issue of teenage binge-drinking in town centres up and down the country. You would be very wrong. Young people drinking too much is a problem. But it is not the biggest drink problem Britain faces. The real problem comes in the form of our hidden alcoholics. Back in my hard-drinking days I was one of them - professional, successful on the surface, with a good job, a steady relationship, a mortgage, nice holidays, lots of friends. But I was heading for a very big fall. The Office for National Statistics tells us that the professional classes are now the most frequent drinkers in the country and that 41% of professional men drink more than the recommended daily limit of three to four units at least once a week. Women are also drinking much more than they used to, with alcoholic liver disease now split evenly between the sexes. My own drinking reached its peak while I worked in Fleet Street in the 1980s - a time when the pub was an extension of the office. Anne Robinson, one of my colleagues on the Daily Mirror back then, was one of the many casualties of the hard-drinking culture. Reflecting back on the days before she too gave it up, Anne said: "It was just a sea of alcohol. If you were editing the paper, people just came in to your office to empty your drinks cabinet." Annie has been dry for years. I paid a heavy price for the same sort of lifestyle when my drinking, coupled with depression, triggered a mental breakdown that landed me in hospital. It forced me to confront my drinking, and by 1986 I'd stopped and started a slow road to recovery. Since then, even in newspapers, Britain's boozy workplace culture has largely disappeared. 24-hour mistake? Yet, paradoxically, more people are being treated for alcohol problems. Recent figures show that nearly 9,000 people die each year in the UK from alcohol-related diseases. Perhaps more alarmingly, liver disease in general is the only major cause of death in Britain that is on the rise, year after year - claiming 100 lives every week - whereas mortality for all the smoking diseases is falling dramatically. Find out more Panorama: Britain's Hidden Alcoholics BBC One, Monday 20 February at 20:30 GMT Then available in the UK on the BBC iPlayer That Britain has a problem with drink is highlighted not just by the figures, but by the fact that the government is busy devising a new strategy to address alcohol-related ill-health. David Cameron has signalled his appetite for reform, including the possibility of minimum pricing as already being taken forward in Scotland, and tougher rules on promotion and marketing. So how did we get here? Well, as with so much of our recent history, the answer lies in Europe. With closer ties came cheaper travel and a newly developed taste for all things European, wine included. Then came the booze cruises to France and the birth of a seemingly unquenchable British thirst. Since 1970, our consumption of wine has gone up five-fold, according to the Beer and Pub Association. We now consume 1.6 billion bottles a year (not counting the ones we drink when we go abroad). It has gone from a middle-class luxury to an everyday part of middle-class life. Anne Robinson remembers a "sea of alcohol" in the newsroom Though ultimately individuals have to take responsibility for their own relationships with alcohol, governments have to set the framework, which is why the planned new strategy is so important. I defend virtually everything done by the government I worked for under Tony Blair. I confess however, as he and Tessa Jowell will confirm, that I was never a big fan of the laws to introduce 24-hour licensing, surely one of the factors in the troubled relationship between Brits and booze. I had left Downing Street by the time the law came in, but it had been mooted for some time before and I never really bought the argument that Britain would suddenly become a continental-style drinking nation. Cheap booze I think we have always had this tendency, where there is drink, to drink it to excess. Did it make things worse? Was it a mistake? On the one hand it is quite nice to have a sense of London and other cities being more European in their approach to drink. But I think it is entirely possible to see a link between increased availability of alcohol and our increased consumption. Britain is, after all, the nation of the gin epidemic - back in the 18th Century. While in 1914, the government had to bring in the Defence of the Realm Act because our own drinking was deemed a threat to our ability to defend ourselves in war. Health campaigners cite those as the first major British drinking crises. They believe we are now facing the third. The big shift in recent times has been the rise of drinking at home, which is why the binge-drinking stereotype is neither accurate nor helpful. The issue is largely about price. Pubs charge a lot for a pint. Supermarkets don't. It is a sad paradox that the decline in pubs has come alongside what seems to be a rise in drinking and alcohol-related problems. In 1970, 90% of all pints were poured in a pub. Today, it is only 50% - the other half are bought much more cheaply in supermarkets and off-licences. The government has to do its bit. But in making a film about Britain's relationship with drink, and in meeting some of the hidden alcoholics, I met people who had each come to their own arrangement with alcohol. For most, the answer is complete abstinence, or complete loss of control. I too said no for 13 years, but then I started having the odd drink again. This time, I feel as though I am more in control. To be frank, it would be hard not to be. Alcohol facts 10m people in England drink more than recommended Daily units men: 3-4 Daily units women: 2-3 New advice is to abstain from alcohol for two days a week Source: Drinkaware But, having met others as they underwent rehabilitation treatment, I do wonder if I am doing the right thing. Partly I am testing myself, having one or two so I can then enjoy the satisfaction of being able to say "No". I also like being able to be "normal" like other social drinkers, just have the odd one and then call it a night. I cannot say I have not drunk since first falling gently off the wagon in 1999. But I can say I have never been drunk, never had a hangover, never touched spirits and never felt the loss of control that had me hospitalised prior to my 13-year unbroken dry spell. The psychiatrist who I see for my depression thinks that even occasional drinking on my part is a bad idea, and interestingly, in making a documentary on the subject, I did once again stop drinking altogether, not least perhaps as a result of the tour of Queen Mary's Hospital anatomy department, where I was shown a few damaged livers. I do feel that my own relationship with alcohol is more secure. And while government has a role to play in setting rules and regulations on responsible drinking, on a certain level I think that our connection to alcohol is a deal that each of us has to make with ourselves. I hope this film helps some of Britain's drinkers to do that.

210,000 people face alcohol death risk, warn doctors

 

Failure to reform alcohol laws could lead to 210,000 preventable deaths in England and Wales in the next 20 years, doctors have warned. They are putting pressure on the government ahead of its "alcohol strategy" for both countries, expected in the coming months. Writing in The Lancet, doctors said the UK was at a "potential tipping point". Prime Minister David Cameron has already vowed to tackle the "scandal" of drunkenness and alcohol abuse. The projected mortality figures comes from Prof Ian Gilmore, a former President of the Royal College of Physicians, Dr Nick Sheron, from the National Institute for Health Research and members of the British Society of Gastroenterology. Their figure of 210,000 is a slight reduction from their previous estimate of 250,000 and represents their "worst-case scenario" of no change to alcohol policy. "It remains entirely within the power of the UK government to prevent the worst-case scenario of preventable deaths," they wrote. The figures for England and Wales suggest 70,000 of the deaths could be from liver disease and the rest from accidents, violence and chronic illnesses such as high blood pressure, stroke, heart disease, breast cancer and cancer of the gastrointestinal tract. 'Tipping point' They were critical of the "responsibility deal" in England, which are voluntary agreements with the drinks industry on issues such as promotions and labelling. Continue reading the main story “ Start Quote What we have to accept is that doing nothing is no longer a responsible option” Eric Appleby Alcohol Concern This was compared to the Scottish government's approach such as a minimum price per unit of alcohol. The group said: "We are at a potential tipping point in the UK in taking on the shameful, preventable loss of life caused by alcohol. "The potential prize of reversing this tragic toll of alcohol-related deaths is there for the taking." The Department of Health will publish its alcohol strategy for England later this year. Selling alcohol below cost price is to be banned in England and Wales from 6 April. However, ministers are expected to go further in the forthcoming strategy, recommending a higher minimum price for drink. The chief executive of Alcohol Concern, Eric Appleby, said: "What we have to accept is that doing nothing is no longer a responsible option for alcohol policy, and that trying to 'nudge' drinking culture through information and persuasion has proved to be little better than doing nothing. "We can see from the example of other countries that drinking patterns really can change, the challenge is there for the government to start the process now through the Alcohol Strategy." Henry Ashworth, chief executive of the Portman Group, which also represents UK drinks producers, said: "It is really important that we put this report in context. "The vast majority of people drink responsibly. Painting doomsday scenarios won't help reduce alcohol misuse and calling for Soviet Union style population controls cannot do anything but alienate the vast majority of people who already drink within Government guidelines. "We agree with the Prime Minister that strong partnerships are essential to tackle the minority who use alcohol recklessly and drinks producers are committed to supporting this approach." The public health minister, Anne Milton, said: "As the Prime Minister said earlier this week, we are determined to tackle the scandal of alcohol abuse. People that misuse alcohol endanger their own lives and those of others. "It costs the NHS £2.7 billion per year and in our forthcoming alcohol strategy we will set out our plans on how to deal with the wide range of problems and harms it causes."

Misery among heroin addicts in Afghanistan

 

U.N. Secretary General Ban ki-moon said Thursday that Afghanistan will never be stable unless it tackles its drug problem. He spoke at an international conference in Vienna. Ninety percent of the world's opium originates in Afghanistan's poppy fields -- and much of that is turned into heroin. CBS News contributor Willem Marx took a look at the problem. Beneath a notorious bridge in downtown Kabul, a human tragedy festers. For more than a year now, hundreds of heroin addicts have lived there -- an ancient opium den in a modern urban sewer. Thousands more drop in each day to buy, smoke and inject their daily fix. "How do you react when you see that level of misery?" Marx asked Jean-Luc Lemahieu, who heads the U.N. Office on Drugs and Crime for Afghanistan. "Appalling, appalling," he said. "And even more appalling, it is happening just below and in front of us." Lemahieu said with ever more users injecting their drugs, there's a troubling new statistic. Around 1 in 14 of Afghanistan's drug users is now believed to be HIV positive. And with addicts sharing needles, that number is soaring. This is how an HIV epidemic brews. We watched as men reused bloody syringes again and again -- so many, that we had to walk carefully among the addicts for fear of treading on an errant needle. "Each day my life was getting worse and worse," said Abdulrahim Rejee, a former heroin user who crawled out of this despair a year ago. Today he lives with nine other recovering addicts in a shared home. Abdulrahim credits a pilot program involving methadone, a heroin substitute that requires no needles. It is widely viewed as the best defense against the spread of HIV here. "I feel my life has changed 100 percent," he said. "I have rejoined my family, and I feel very healthy." But methadone is available for just a fraction of Afghanistan's addicts -- Abdulrahim and 70 others. "We need to expand the delivery of that service to a lot more addicts than what we are able to do today," said Lemahieu. The only other option here is to go cold turkey at a detox clinic. Under the bridge one morning, Marx saw an addict collapse from an overdose. Abdulrahim jumped in to resuscitate the struggling man. "When I go to that bridge," Abdulrahim told Marx, "I want to help those people, that they can live like me." The man barely survived barely, But with limited care available, he lived only to shoot up another day. This misery persists, while a deadly virus continues to spread.

'Britain's war against Afghan opium production is failing'

 

Britain’s war against opium production in Afghanistan is being lost, according to UN Secretary General Ban Ki-Moon, with outputs of the class-A drug soaring to record levels in the past decade despite western intervention.

The final hours, Whitney Houston wandered erratically around the lobby of the Beverly Hilton Hotel.

DISCLAIMER:Text may be subject to copyright.This blog does not claim copyright to any such text. Copyright remains with the original copyright holder.In her final hours, Whitney Houston wandered erratically around the lobby of the Beverly Hilton Hotel. Near the end of his life, the onetime matinee idol Elvis Presley was bloated and glassy-eyed. Amy Winehouse became notorious for stuttering and slurring onstage.

And when these bright stars fell to drug and alcohol addictions, the public was devastated, but not completely surprised. With so many entertainers dying too young from substance abuse issues, it raises the question: Is addiction linked to superstardom?

"I don't think stars are more likely to get addicted than other people," said Dr. Jeffrey Berman, a board-certified addiction psychiatrist and medical director for addiction services at Bergen Regional Medical Center. "But I think the people around them tend to tolerate their behavior using drugs and alcohol."

Celebrity drug abuse draws the most public attention, said Ridgewood addiction specialist Dr. Michael Gentile, but addiction is everywhere in society. "Drug and alcohol addiction knows no boundaries – it's prevalent across the board. From my point of view, compare that to an inner city and the general population, and they're pretty much even," he added.

It's just that tales of musicians partying hard and abusing drugs and alcohol have become part of pop culture lore.

"In the arts, there's a lot of downtime," said Tenafly's Gene Bowen, who spent 15 years as a rock-and-roll road manager and addict. After cleaning up, he founded Road Recovery, a non-profit organization that unites musicians and other entertainment professionals who've battled addiction and other adversities to mentor at-risk youth. "One of the things about addiction, we need structure."

It's not just culture and environment that create an addict; there are plenty of musicians who are clean. But is there something inherent in an artist – for example, Houston's charismatic personality – that makes her want to continually get high?

Not really, according to Berman. "I think the only personality you can generalize is they have some feeling of entitlement and that they're special. Sometimes they don't feel the need to suffer feelings and want to instantly change their mood," he said.

The irony is that the rich and famous have access to the best treatment available, yet their entourages can enable their destructive behavior.

"One of the things that seems to happen with very successful people is that they are insulated and have enormous resources and a lot of people around yessing them," Bowen said.

It looks as though Whitney had got to a stage where she was using Xanax like clockwork. “Mixed with alcohol, it is known to be a killer. It’s the same deadly combination that killed Heath Ledger.”

 

DETECTIVES will quiz up tonine doctors they believe could have supplied Whitney Houston with a lethal cocktail of prescription drugs. The superstar singer died in her hotel bath on Saturday after taking a host of powerful sedatives. And last night, sources claimed her drug taking had spiralled out of control in recent months, turning her into a virtual “zombie”. The 48-year-old had become a tortured recluse, regularly spending most of the day in bed before emerging in the evenings to party. Police are now anxious to find out how a recovering crack addict with a long history of drug and alcohol abuse was able to get hold of such a vast quantity of pills. A source said: “The only way Whitney could function was on a cocktail of different drugs – uppers, downers, sleeping pills, painkillers, a whole medicine cabinet. “She was living like a zombie – always on medication. The more she took, the more she needed. “With alcohol in the mix, this was a tragedy waiting to happen. But she needed quite a network to obtain drugs in that kind of number.” Officers will begin their probe at the infamous Mickey Fine pharmacy in Beverly Hills, where Michael Jackson got his prescription drugs. It’s believed at least some of Whitney’s medication was obtained there. Bottles of Lorazepam, Valium and Xanax were found in her suiteat the Beverly Hilton Hotel. All three are used to treat anxiety disorders, while Valium can also ease alcohol withdrawal symptoms and muscle spasms. It’s thought Whitney was also taking painkillers and sleeping pills. Police and the LA county coroner are working on the premise that a combination of drugs and alcohol caused the star to become heavily sedated or overdose – ultimately leading to her death. It’s also possible that she suffered a heart attack caused by an adverse reaction to her medication. An autopsy was performed on Sunday but officials said they wouldn’t have any definitive answers until drug tests are completed in several weeks. Another theory was that the singer took sedatives, fell asleep and drowned in the tub. Police say Whitney was found underwater and unconscious. But the coroner told her family there was not enough water in her lungs to conclude that she had drowned. Detectives are expected to treat the investigation the same way they handled Michael Jackson’s death. They discovered dozens of doctors were supplying the King of Pop with different prescription drugs. Jackson’s personal physician, Conrad Murray – who administered the fatal dose of hospital anaesthetic Propofol – was later found guilty of manslaughter. Yesterday, it emerged that Whitney had visited a doctor at a private clinic in Beverly Hills just two days before she died. US X Factor winner Melanie Amaro revealed that she bumped into Whitney at the surgery on Thursday. Whitney is also known to have visited other private clinics on February 7 and February 2 – and it’s possible that she visited other doctors as well. It’s thought police will also probe whether she used friends, staff or hangers-on to get prescriptions in their own names and then hand over the pills. Detectives are piecing together Whitney’s physical and emotional state before she died. She seemed to have slid back to the days when she and husband Bobby Brown regularly abused drugs and alcohol in week-long party binges. On Thursday night, Whitney looked wild-eyed and dishevelled as she left Hollywood’s Tru nightclub, where she joined revellers at a bash thrown by American singer Kelly Price. She had scratches on her wrist and blood running down a leg and witnesses say she reeked of booze, sweat and cigarettes. Whitney downed tequila at the party and went berserk when she saw her on-off toyboy lover, singer and actor Ray J, 31, talking to another girl. One witness said the former powerhouse vocalist who sold more than 170million albums worldwide seemed “wasted”. A music industry source said: “It looks as though Whitney had got to a stage where she was using Xanax like clockwork. “Mixed with alcohol, it is known to be a killer. It’s the same deadly combination that killed Heath Ledger.”

Pattaya's foreign criminals feel the heat

 

 

This is why the Provincial Region 2 has established the Transnational Crime Coordination Centre (TNCC) to deal directly with foreigners who come to Thailand to commit crimes. The existence of the centre has shed some light on how diverse the transnational gangs in Pattaya are and how their illegal businesses in this tourist centre have flourished. French nationals Nagim Hassainia, 33, and Samir Raihane, 41, who are suspects in a credit card fraud case, were arrested on Feb 2. The suspects were nabbed at a hotel in Pattaya after police found them withdrawing money from an ATM using forged credit cards containing information stolen from other countries. They sent 70% of the money back to their networks in France and took the rest of the money, the TNCC said. At least 10 members of the French gang are thought to be still on the loose. Some of them are responsible for stealing credit card information and ATM pins using a skimmer. Police seized 31 fake credit cards and 125,000 baht from the suspects. "This case could cause serious damage to Thailand's reputation," said Pol Lt Gen Panya Mamen, chief of the the Provincial Police Region 2. He said there were many foreign criminals on Pattaya's streets _ and one way to better deal with them was to improve the capacity of the TNCC, especially its ability to gather information and put it into the police database. "I have to admit there are a lot of foreign criminals who are tourists in disguise. Some are here to work with their Thai counterparts, while others act on their own," Pol Lt Gen Panya said. "Some are paedophiles. Others are criminals wanted by police in other countries yet come here pretending to be language teachers. All this makes Pattaya sound like a horrible city." Pol Lt Gen Panya hoped the Provincial Police Region 2 would achieve its goal of significantly decreasing the number of "unwanted visitors" in Pattaya within six months. The Provincial Police Region 2 is also stepping up efforts to strictly enforce the Immigration Act in which foreign suspects who are found to have criminal records or believed to be involved in a crime will have their visa nullified immediately and be extradited. These suspects will also be blacklisted by Thai immigration authorities. "They normally move around from Pattaya to Phuket, Koh Samui, Chiang Mai and then return to Pattaya again. If we can pool information, it will become easier to track them," Pol Lt Gen Panya said. Different gangs committed different crimes, ranging from theft to murder, he said. Pol Lt Gen Panya said some French gangs were known to be involved with fake credit cards and ATM cards. He said some Colombian gangs were involved with theft, whereas some Taiwanese gangs were linked to call centre scams. Pol Lt Col Chitdecha Songhong and Pol Capt Prajakpong Suriya of the TNNC, who arrested members of a French gang, agreed that inter-agency cooperation was crucial to uprooting a transnational gang. Pol Capt Prajakpong said it was difficult to locate foreign suspects even if police had pictures of them because they were frequently on the move and it was not easy to find information about them. "Pattaya is a popular criminal base because it's a hub of tourists and expatriates and the city has a lot of diamond and gold shops," he said. "The city also has many unregistered or illegal residential services which allow those criminals to stay here and hide away from immigration authorities." The TNNC is working with embassy officials in Pattaya and local banks to keep an eye on foreigners who come to the city to commit crimes.

The founder and leader of glam rock group, ‘Loco Mia’, 46 year old Xavier Font

The founder and leader of glam rock group, ‘Loco Mia’, 46 year old Xavier Font, will sit on the accused bench in the Barcelona courts on Tuesday accused of trafficking in the drugs poppers and ecstasy.
The prosecutors’ office is calling for a seven year prison sentence and a 7,500 € fine for the artists and businessman.

Font remains the group’s representative although it now has other members, and announced the sale of the drugs on a webpage in which two mobile phone numbers were published. Clients who called, if they lived in Barcelona, could collect the drugs in one of Font’s two homes in the city, and if they lived elsewhere the drugs were sent by courier and paid for by bank transfer or on delivery.

The prosecutor says they have evidence he was carrying out this activity at least between January 26 and February 4, when the Guardia Civil carried out a search of Font’s home in Calle Fontanella in Barcelona.

110 bottles of poppers were found, along with 116 pink pills thought to be ecstasy. The sale of both drugs is prohibited in Spain.

Along with Font a 28 year old man, L.O.R.A. from El Salvador was arrested, and he faces the same charges.

Arrest made in death of Dartmouth student in Spain

Spanish police have arrested a man in Barcelona in connection to the Jan. 7 death of a Dartmouth College student Crispin Scott. Scott, who was to graduate from Dartmouth in 2013, was found dead in Barcelona, Spain, days after arriving in the city to participate in a study abroad program offered through Portland State University. Early autopsy reports indicated drug overdose was the cause of death, according to the Spanish newspaper El Periodico de Catalunya on Saturday. However, the final autopsy report revealed the amount and type of drugs, a powerful barbiturate, indicated his death was not the result of a night of partying as first suspected of the college student, though friends and family said he was a good student and athlete. The final autopsy results caused police to investigate the background of the landlord of the apartment Scott had been found in. The landlord had acted cold during the investigation, police had noted, according to El Periodico. Police learned the man, whose name has not been released, had been accused by a young man in 2009 of drugging and violating him. Police arrested and charged the landlord with murder on Wednesday, according to El Periodico. He is accused of giving Scott a drink containing a dissolved barbiturate. After police searched the man's home and another Barcelona apartment he frequented they found two dozen photos of young people, unconscious and in different states of dress and undress. Police believe he had photographed them after giving them a mixture of tranquilizers. Police believe these young people had been sexually assaulted by the man and that possibly this landlord is a serial rapist. Scott had just arrived in Barcelona to participate in a two-month Academy of Liberal and Beaux-Arts program sponsored by Portland State University when he was found dead.

Whitney Houston dead: coroner confirms singer was found in hotel bathtub

 

Police requested that no details about the singer's autopsy be publicly released, Assistant Chief Coroner Ed Winter told reporters on Sunday afternoon. He said toxicology results would take weeks and the results were needed to determine how Houston died. Dr Winter declined to release any details about what investigators found in the room, but said coroner's officials were not ruling out any potential causes of death. He said there were no signs of trauma on Houston's body. Detective investigating the death of Whitney Houston on the eve of the Grammy Awards are pursuing a theory that she accidentally drowned in the bath in her luxury hotel suite after taking prescription drugs and drinking heavily over the previous two evenings.

Demi Moore’s 911 call released: Star ‘smoked something’

 

The call made to emergency services when Demi Moore was taken to hospital on Monday night has just been obtained and it seems to imply actress was convulsing after smoking a mystery substance. Advertisement >> A friend of Demi can be heard at the beginning of the 911 call on US website TMZ.com trying to get an ambulance to the star’s Beverley Hills home. There is confusion as the phone operator tries to determine which emergency service is needed and where it should be dispatched from. Once paramedics are on their way, the operator asks Demi’s friend what has happened. She replies: “She’s smoked something. It’s not marijuana but it’s similar to incense and she’s been having convulsions of some sort.” After informing the operator that Demi is 49 years old, her friend goes to sit with her, whilst remaining on the phone. She reports that Demi is “semi conscious and barely breathing” and also still convulsing. She is asked if the incident was accidental and she replies: “She smoked something but the reaction was accidental.” The phone is then passed to someone else who is asked about her breathing. “No, it’s not normal, more shaking” the second friend tells the operator. “She’s burning up. She smoked something. She’s been having some issues lately with some other stuff. I don’t know what she’s been taking.” The pal also says that Demi is unable to speak but has squeezed her hand and is still convulsing, so they are holding her down. The operator tells them not to do this, but to hold her head and keep her airways open. When the friend is asked if she has done this before, she replies: “I don’t know, there’s been some stuff recently that we’re all just finding out.” At the end of the call, a male friend comes on the line and reports that Demi is “much calmer” and is now “breathing fine” while sitting up and quietly talking.

Free booze for alcoholics makes perfect logic, but no sense

 

As the old adage has it, if you live long enough, you see everything. In the world of substance abuse and addiction, “everything” was in the news today. A group from Vancouver’s notorious hub of drug addiction and policy experimentation, the Downtown East Side, is proposing that a publicly funded, peer-run drinker’s lounge dispensing free legal alcohol to alcoholics be instituted as a means of harm reduction. The Eastside Illicit Drinkers Group for Education, whose spokesman, Rob Morgan, an alcoholic from a First Nations reserve near Terrace, B.C, sees the idea as the natural next step in Vancouver’s famous harm reduction movement. The lounge would be modeled on Insite, the safe injection site whose mandate is not to rehabilitate addicts, but to reduce the rates of disease and death caused by unhygienic consumption and unsupervised overdoes. Mr. Morgan’s logic is impeccable. Desperate alcoholics will drink anything with alcohol in it; they will drink hand sanitizer acquired from “dealers” who steal them from hospitals, as Mr Morgan has; they will share disease-ridden bottles; they sometimes freeze to death in an alcoholic stupor; and for only $3, and some water dilution, will consume 30 standard drinks from a 250 ml bottle of 95% rubbing alcohol. The ravages produced on the body by such a regime certainly rival any depredations short of AIDS suffered by drug addicts.

Internet addiction changes brain similar to cocaine

 

Can a person be truly addicted to the Internet? A new brain scan study shows not only can that be the case, but also that Internet addiction might cause the same brain changes that are seen in alcoholics and drug addicts. For the study, published in the Jan. 11 issue of PLoS One, researchers studied 17 men and women who were diagnosed with Internet addiction disorder (IAD) and compared scans of their brains to scans of 16 healthy people who weren't addicted to the web. Study participants were between the ages of 14 and 21 and lived in China. Video Game-Obsessed Mom Neglects Kids, Starves Dogs Are social networking sites turning teens into substance abusers? The researchers found more patterns of  "abnormal white matter" on brain scans of Internet addicts, compared with scans of non-addicts. White matter areas in the brain contain nerve fibers that transmit signals to other parts of the brain. These changes showed evidence of disrupting pathways related to emotions, decision-making, and self control. The researchers said earlier studies have found similar white matter changes in the brain scans of people addicted to alcohol, cocaine, heroin, marijuana, meth, and ketamine (also known as "Special K"). "The results also suggest that IAD may share psychological and neural mechanisms with other types of substance addiction and impulse control disorders," the researchers wrote in the study. Professor Gunter Schumann, chair in biological psychiatry at the Institute of Psychiatry at King's College, London, told BBC News that he's come across similar findings in brain scans of video game addicts. "For the first time two studies show changes in the neuronal connections between brain areas as well as changes in brain function in people who are frequently using the Internet or video games," he said. Dr. Henrietta Bowden Jones, consultant psychiatrist at Imperial College in London, who runs the U.K.'s only clinic for Internet addicts, said hardcore gamers are more likely to be addicted to the Internet. "The majority of people we see with serious Internet addiction are gamers - people who spend long hours in roles in various games that cause them to disregard their obligations," Jones told The Independent. "I have seen people who stopped attending university lectures, failed their degrees or their marriages broke down because they were unable to emotionally connect with anything outside the game." According to the independent, an estimated 5 to 10 percent of Internet users are unable to control their usage and are considered addicts.

Gut hormone may be new weight loss tool, study says

 

An appetite-suppressing hormone produced by the body that is used to treat type 2 diabetes can lead to weight loss in overweight or obese patients, says a new study. The research, published Tuesday at bmj.com, also found that glucagon-like peptide-1, or GLP-1, reduces blood pressure and cholesterol levels. GLP-1 is a hormone secreted by the gut when we eat. A form of GLP-1 that is injected has emerged as a new treatment for type 2 diabetes for its ability to regulate blood-sugar levels. But researchers have now found that the hormone can help with weight loss by curbing the appetite, thereby reducing food intake. The Danish study, which included data from 6,000 patients who took part in 25 randomized controlled trials, found that in addition to lowering blood pressure and cholesterol -- as well as regulating blood sugar -- GSP-1 also helped with weight loss. Study subjects lost up to eight pounds over a four-month period. While both patients with and without type 2 diabetes lost weight, the weight loss was more pronounced in patients without the disease. "We see a sustained effect on body weight throughout the trials, 25 trials," researcher Dr. Tina Vilsboll, head of diabetes research at the University of Copenhagen, told CTV News. "So it is not just a coincidence, it is efficacious on body weight." The findings are especially significant because other diabetes medications often cause patients to gain, rather than lose, weight. The researchers write that further study is needed to determine if GLP-1, which costs about $400 per month, should be prescribed for overweight or obese patients without type 2 diabetes. According to Vilsboll, researchers will know within the next two to three years if GLP-1 can be more widely prescribed solely as weight-loss treatment. The study has led some experts to urge caution, however. In an accompanying editorial, obesity specialist Dr. Raj Padwal of the University of Alberta points out that the weight loss was modest. As well, the hormone can produce side effects, such as nausea and vomiting, and comes with a possible risk of damage to the pancreas and the thyroid. "While these results highlight the weight-reducing benefits, they should not alter current practice," Padwal wrote. According to Padwal, "modification of diet and lifestyle remains the cornerstone of the treatment of type 2 diabetes." Vilsboll said the hormone is not a cure for type 2 diabetes. However, combined with lifestyle changes, it could have a major impact on the health of patients. Dr. Ravi Retnakaran of Toronto's Mount Sinai Hospital is also studying the hormone, and says the research "is an encouraging sign because weight control is an important part of the management of diabetes."

Recovering alcoholic Matt Maden: I began drinking at 10 and now I'm facing death at 26

 

Matt Maden, now 26, has been living on borrowed time since he was diagnosed with liver cirrhosis five years ago. Despite his desperate need he has only a 20 per cent chance of getting an organ because of the growing demand. ‘It’s really scary living with the knowledge that the odds are so heavily against you,’ he said. His condition was detected when he spent two weeks in hospital in an alcohol-induced coma – but even then he refused to believe he had a problem. ‘My immediate thought was, “It’s not the drink”,’ he said. The first time Mr Maden got drunk was at 15. ‘I remember waking up the next morning and my first thought was, “When can I do that again”,’ he said. Within a year he went from drinking eight cans of lager in a session to 16 in order to get a buzz. ‘After a couple of years I’d have to have maybe a bottle of spirits to go along with that,’ he added. ‘For a lot of years alcohol gave me  confidence. Little did I know it would actually turn on me and it would start to control me.’ After his health scare Mr Maden left his home in Oxford to check into a rehab clinic in Bournemouth and has not touched a drop since 2007. His physician, Dr Varuna Aluvihare, from King’s College London, believes the binge-drinking culture is behind the increasing number of young people needing liver transplants. ‘Tragically, every year we fail to keep someone like Matt alive,’ he said.

Money spent on nicotine patches 'goes up in smoke', says survey

 

Those who go cold turkey have just as much chance of quitting the habit long-term, the study published on Monday added. A total of 787 adult smokers trying to quit were followed over five years by researchers at Harvard School of Public Health. One in three relapsed with the numbers spread equally between those going ‘cold turkey’, those using nicotine patches, gums or sprays, and those combining nicotine replacement with counselling. Heavy smokers who used nicotine replacement products without any professional therapy were twice as likely to relapse. Lead author Hillel Alpert said: ‘Some heavily-dependent smokers perceive nicotine replacement therapy (NRT) as a sort of “magic” pill. ‘Upon realising it is not, they find themselves without support in their quitting efforts, doomed to failure.’ But the findings sparked a backlash from the NRT industry, which is worth £150million in Britain and £520million in the US. GlaxoSmithKline, which makes Nicorette gum, said studies show NRT products, combined with support, ‘can double’ smokers’ chances of quitting

spokesman of the ROP said that more expatriates than Omani nationals are involved in drug trafficking.

 

An increasing number of drug abuse and drug trafficking cases are being registered in the Sultanate over the past few months. The trend has seen a spiralling increase following the Royal Oman Police (ROP) campaign to arrest the drug traffickers and abusers, say legal experts. A spokesman of the ROP said that more expatriates than Omani nationals are involved in drug trafficking. The police have smashed a number of drug trafficking gangs operating in the Sultanate and last week six persons were hauled up for being involved in dealing with contraband narcotics. According to the courts, most of the drug abusers are also involved in criminal activities and many of them have admitted to having robbed shops and houses in order to buy narcotics. Another growing phenomenon being noticed by the police is that some people who have consumed drugs or steroids refuse to take the medical examinations. They also refuse to give blood or urine sample to escape the charges being framed against them and sometimes indulge in violence with security men. Another unusual development witnessed by the courts is that family ties have come under increasing strain due to drug-related activities of the youths. Some parents have even reported to the police to take action against their children involved in misusing narcotic substances. “These youths have become not only a social menace, but a threat to their own families,” said a senior ROP officer. Meanwhile, the ROP has stepped up its efforts to combat the drug menace in the Sultanate and has set up a specialised team to bust the drug dealing gangs and consumers of narcotics. The punishment for drug trafficker is more than the abuser according to the penal law of the Sultanate. The security forces have been alerted about drug activities and directed to take preventive steps. The Coast Guard has been equipped with new boats to foil any drug smuggling attempts. In addition, the Royal Air Force of Oman has been given advanced helicopters to monitor Oman’s territorial waters and support other security units in the Sultanate. A senior source from the ROP said that the drug traffickers were using illegal immigrants as couriers to smuggle drugs into the country. Recently, the Majlis Al Shura also discussed the menace of drug abuse in the society. The official statistics indicate that the number of drug-related crimes increased to 895 last year compared to 688 in 2009. The number of accused was 1,417 and the amount of drugs seized by the ROP was 314 kg. The government has also taken initiatives to support the drug abusers to give up their habit. The ROP has plans to open the Al Masra Hospital for treating the addicts and officials hope that the hospital would become operational soon.

Counsellors Forum: DREAMWARRIOR spiritual teacher who is deeply committed to helping others break through to the joyous experience of living in the NOW.

 

DREAMWARRIOR teaches how to become fundamentally present and how to arise in mastery of your mind and ego, so that you are no longer involuntarily pulled out of Presence. teaches that the fully awakened state of consciousness is available now. It is not something that occurs in the future. It is already here, waiting to be revealed. As you awaken into the present moment, your thoughts will stop, your mind will fall silent, and you will awaken to an inner silence and peace that is beyond understanding. You will begin to encounter what the mystics and Masters have been speaking of for centuries.

Are you addicted to your smartphone?

 

When Adrian Weldon has a few minutes to spare, he's probably going to use them to text. "I came here to kill time and text," he said, sitting at Lakebottom Park Thursday afternoon. "At least it's not driving and texting." Weldon said he uses his phone mostly for texting, sending quick messages while he's at work and can't call people on the phone, and when he's bored. If you ask him if he's addicted, he says he's not sure. "My girlfriend says I am," he said. If Weldon is addicted to his phone, he's not alone. While addiction to apps or text-ing is not a recognized medical condition, there have been numerous studies produced on whether the technology causes more harm than good. A study by Case Western Reserve School of Medicine found that teens who spend a lot of time on texting or on social media are also more like to use drugs or alcohol and get into fights. Using a smartphone or computer just before bed can lead to sleep loss, according to a study from the National Sleep Foundation. But ignoring your phone can be difficult. A recent article in the New York Times by author and brand consultant Martin Lindstorm claimed the top three most powerful affecting sounds in the world are baby giggles, the Intel chime and a vibrating phone. Weldon confesses to feeling lost without his phone. He never turns it off. "Even when it's charging, it's on," he said. "I left it once Advertisement and went home on my lunch break just to get it." Smartphones also can be habit-forming, according to a study by Helsinki Institute for Information Technology and Intel Labs. Researchers found that smartphone users in the U.S. and in Finland checked their phone repeatedly throughout the day, usually for less than 30 seconds. They observed that the checks are usually triggered by the same things -- a person may always check email while commuting or always check the news when bored. "It's a boredom buster," said Mary Virginia Wehrenberg. She said she typically uses her smartphone truly as a phone, but the apps and texting also poses a great distraction when you're stuck waiting for something. Sharlene Brown said she tries to ration the time she spends on her smartphone. She's a fan of Words with Friends -- a popular Scrabble-like game -- and frequently plays using a dictionary app so she can check to make sure she's using real words. "I don't win as often but I love it." She said it's easy to waste time on her phone, especially on rainy or lazy days. Her kids -- ages 8 and 4 -- like playing games on her phone, too, but she only lets them use it for 15 to 30 minutes a day. "I do limit the time," she said. "Children shouldn't have it all the time." But there are benefits to the apps and texting a smartphone offers. Brown said there are math and word games available for her kids, like Quizard, an app that lets you create your own educational flashcards. "It's interactive. They get an immediate response." Texting also gives her more time with her kids, because she's not always on the phone. "It's an easier way to communicate. You send them a quick text," she said. "You don't want to take away from time with kids."